A new route to the nucleus

Elife. 2022 Oct 13:11:e83308. doi: 10.7554/eLife.83308.

Abstract

A newly discovered pathway suggests histone proteins H3 and H4 are imported into the nucleus as individual units rather than joined together as heterodimers as was previously thought.

Keywords: biochemistry; chemical biology; chromatin; chromosomes; gene expression; histone; histone chaperone; human; importin; nuclear import.

Publication types

  • Editorial
  • Comment

MeSH terms

  • Active Transport, Cell Nucleus
  • Cell Nucleus* / metabolism
  • Histones* / metabolism

Substances

  • Histones