Evaluation of the Antibacterial Efficacy of QMix and AgNP Solutions in Root Canals of Primary Molars: An In-Vitro Study

Dania Alkhourbotly; Mohamed K Altinawi; Rouaida Abou-Samra; Hasan M Alzoubi; Abedulrahman K Ebrahim

doi:10.7759/cureus.28877

Evaluation of the Antibacterial Efficacy of QMix and AgNP Solutions in Root Canals of Primary Molars: An In-Vitro Study

Cureus. 2022 Sep 7;14(9):e28877. doi: 10.7759/cureus.28877. eCollection 2022 Sep.

Authors

Dania Alkhourbotly¹, Mohamed K Altinawi², Rouaida Abou-Samra³, Hasan M Alzoubi¹, Abedulrahman K Ebrahim⁴

Affiliations

¹ Department of Pediatric Dentistry, Damascus University, Damascus, SYR.
² Department of Pedodontics and Preventive Dentistry, Damascus University, Damascus, SYR.
³ Department of Chemistry and Biochemistry, Damascus University, Damascus, SYR.
⁴ Department of Endodontics, Damascus University, Damascus, SYR.

Abstract

Purpose The study aimed to evaluate QMix²ⁱⁿ¹ and silver nanoparticles (AgNPs) solution in eliminating Enterococcus faecalis (E. faecalis) bacteria within root canals of primary molars. Materials and methods The study sample consisted of 45 extracted primary molars, which were divided into three groups: Group 1 (control) NaOCl 5.25%, Group 2 (experimental) QMix^{2 in 1}, and Group 3 (experimental) AgNPs 4000 ppm. The root canals were sterilized within an autoclave and then contaminated with E. faecalis bacteria. The root canals were irrigated for five minutes in a quantity of 3 ml using a 31-gauge irrigation needle, and then bacterial smears were taken. Results Sodium hypochlorite, AgNPs, and QMix²ⁱⁿ¹ effectively reduced the bacterial count of Enterococcus within root canals of primary molars. There were statistical differences between all groups. QMix²ⁱⁿ¹ solution showed the greatest antibacterial efficacy, then NaOCl solution and AgNPs solution. Conclusion All irrigation solutions used are effective in eliminating E. faecalis. QMix²ⁱⁿ¹ can be considered a good alternative to sodium hypochlorite in irrigation root canals of primary teeth.

Keywords: antibacterial efficacy; enterococcus faecalis; irrigation; primary molars; qmix; sodium hypochlorite.