Complementary dose of COVID-19 vaccination may prevent SARS-CoV-2 breakthrough infection among previously vaccinated HIV positive persons

Przegl Epidemiol. 2022;76(2):147-149. doi: 10.32394/pe.76.13.

Abstract

People living with HIV (PLWH) are a heterogeneous group of immunocompromised persons. Detectable HIV viral load and chronic comorbidities are independently increasing the risk of severe outcomes from COVID-19 among PLWH. We aimed to assess the efficacy and safety of the COVID-19 vaccines in PLWH. A significant increase in S-RBD antibody titers >100 AU/mL was observed when compared the titers measured one week after the 1st dose to titers performed after the 2nd vaccine dose.

Keywords: COVID-19; HIV; prevention; vaccination; viral infections.

Publication types

  • Letter

MeSH terms

  • Antibodies, Viral
  • COVID-19 Vaccines* / administration & dosage
  • COVID-19* / immunology
  • COVID-19* / prevention & control
  • HIV Infections* / immunology
  • Humans
  • Immunization, Secondary
  • Poland
  • SARS-CoV-2
  • Vaccination

Substances

  • Antibodies, Viral
  • COVID-19 Vaccines

Supplementary concepts

  • COVID-19 breakthrough infections