IL-17a is widely considered an inflammatory cytokine, linked to the development and severity of autoimmune diseases such as inflammatory bowel disease and psoriasis. However, a recent report by Konieczny et al. sheds light on a novel protective role of IL-17a in wound healing, adding to the growing list of studies highlighting a noninflammatory function for IL-17a.
Keywords: HIF-1α; immunoepithelial; immunometabolism; interleukin-17a; wound healing; γδ T cells.
Copyright © 2022. Published by Elsevier Ltd.