Bioactive Restorative Dental Materials-The New Frontier

Mary Anne S Melo; Lamia Mokeem; Jirun Sun

doi:10.1016/j.cden.2022.05.005

Bioactive Restorative Dental Materials-The New Frontier

Dent Clin North Am. 2022 Oct;66(4):551-566. doi: 10.1016/j.cden.2022.05.005. Epub 2022 Sep 7.

Authors

Mary Anne S Melo¹, Lamia Mokeem², Jirun Sun³

Affiliations

¹ Program in Dental Biomedical Sciences, University of Maryland School of Dentistry, 650 West Baltimore Street, Baltimore, MD 21201, USA; Division of Operative Dentistry, Department of General Dentistry, University of Maryland Dental School, 650 West Baltimore Street, Baltimore, MD 21201, USA. Electronic address: mmelo@umaryland.edu.
² Program in Dental Biomedical Sciences, University of Maryland School of Dentistry, 650 West Baltimore Street, Baltimore, MD 21201, USA.
³ The Forsyth Institute, Harvard School of Dental Medicine Affiliate, 245 First Street, Cambridge, MA 02142, USA.

PMID: 36216446
DOI: 10.1016/j.cden.2022.05.005

Abstract

Bioactive materials for dental resin restorations are a rising field of investigation exploring treatment strategies for reducing the recurrence of carious lesions. The current effort has been directed toward developing dental materials that can inhibit biofilms and prevent tooth mineral loss. Bioactive resin materials have shown the potential to interfere with polymicrobial consortia in vivo and help maintain the lifespan of restorations.

Keywords: Antibacterial; Bioactive materials; Dental caries; Oral biofilms; Resin composites.

Publication types

Review
Research Support, N.I.H., Extramural

MeSH terms

Biofilms
Composite Resins* / therapeutic use
Dental Caries* / prevention & control
Dental Materials / therapeutic use
Dental Restoration, Permanent
Humans

Substances

Composite Resins
Dental Materials

Grants and funding

R03 DE030562/DE/NIDCR NIH HHS/United States