Clinical and health economic evaluation of a post-stroke arrhythmia monitoring service

Br J Cardiol. 2022 May 31;29(2):15. doi: 10.5837/bjc.2022.015. eCollection 2022.

Abstract

Atrial fibrillation (AF) is a major cause of recurrent stroke and transient ischaemic attack (TIA) in the UK. As many patients can have asymptomatic paroxysmal AF, prolonged arrhythmia monitoring is advised in selected patients following a stroke or TIA. This service evaluation assessed the clinical and potential health economic impact of prolonged arrhythmia monitoring post-stroke using R-TEST monitoring devices. This was a prospective, case-controlled, service evaluation in a single health board in the North of Scotland. Patients were included if they had a recent stroke or TIA, were in sinus rhythm, and did not have another indication for, or contraindication to, oral anticoagulation. A health economic model was developed to estimate the clinical and economic value delivered by the R-TEST monitoring. Approval to use anonymised patient data in this service evaluation was obtained. During the evaluation period, 100 consecutive patients were included. The average age was 70 ± 11 years, 46% were female. Stroke was the presenting complaint in 83% of patients with the other 17% having had a TIA. AF was detected in seven of 83 (8.4%) patients who had had a stroke and one of 17 (5.9%) patients with a TIA. Health economic modelling predicted that adoption of R-TEST monitoring has a high probability of demonstrating both clinical and economic benefits. In conclusion, developing a post-stroke arrhythmia monitoring service using R-TEST devices is feasible, effective at detecting AF, and represents a probable clinical and economic benefit.

Keywords: atrial fibrillation; economic evaluation; recurrent stroke; stroke.

Grants and funding

This project was undertaken as part of a joint working agreement with Daiichi Sankyo Ltd. who funded the R-TEST monitors only. Daiichi Sankyo had no input over the study design, participant recruitment, data collection and analysis, or content of this report and Daiichi Sankyo did not write the report. AG is funded by Inverness and Highland City Region Deal.