Nanomaterials based on thermosensitive polymer in biomedical field

Yingshu Guo; Li Sun; Yajing Wang; Qianqian Wang; Dan Jing; Shiwei Liu

doi:10.3389/fchem.2022.946183

Nanomaterials based on thermosensitive polymer in biomedical field

Front Chem. 2022 Sep 21:10:946183. doi: 10.3389/fchem.2022.946183. eCollection 2022.

Authors

Yingshu Guo¹, Li Sun², Yajing Wang², Qianqian Wang², Dan Jing¹, Shiwei Liu¹

Affiliations

¹ Shandong Provincial Key Laboratory of Molecular Engineering, School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
² School of Chemistry and Chemical Engineering, Linyi University, Linyi, China.

Abstract

The progress of nanotechnology enables us to make use of the special properties of materials on the nanoscale and open up many new fields of biomedical research. Among them, thermosensitive nanomaterials stand out in many biomedical fields because of their "intelligent" behavior in response to temperature changes. However, this article mainly reviews the research progress of thermosensitive nanomaterials, which are popular in biomedical applications in recent years. Here, we simply classify the thermally responsive nanomaterials according to the types of polymers, focusing on the mechanisms of action and their advantages and potential. Finally, we deeply investigate the applications of thermosensitive nanomaterials in drug delivery, tissue engineering, sensing analysis, cell culture, 3D printing, and other fields and probe the current challenges and future development prospects of thermosensitive nanomaterials.

Keywords: bioanalysis; nanomaterials; polymer; sol–gel transition; temperature sensitive.

Publication types

Review