A comprehensive review on the pretreatment and detection methods of neonicotinoid insecticides in food and environmental samples

Yudan Wang; Yanwei Fu; Yunyun Wang; Qian Lu; Haonan Ruan; Jiaoyang Luo; Meihua Yang

doi:10.1016/j.fochx.2022.100375

A comprehensive review on the pretreatment and detection methods of neonicotinoid insecticides in food and environmental samples

Food Chem X. 2022 Jun 22:15:100375. doi: 10.1016/j.fochx.2022.100375. eCollection 2022 Oct 30.

Authors

Yudan Wang¹, Yanwei Fu^{1

2}, Yunyun Wang¹, Qian Lu¹, Haonan Ruan¹, Jiaoyang Luo¹, Meihua Yang¹

Affiliations

¹ Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
² Department of Pharmacy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.

Abstract

In recent years, the residues of neonicotinoid insecticide in food and environmental samples have attracted extensive attention. Neonicotinoids have many adverse effects on human health, such as cancer, chronic disease, birth defects, and infertility. They have substantial toxicity to some non-target organisms (especially bees). Hence, monitoring the residues of neonicotinoid insecticides in foodstuffs is necessary to guarantee public health and ecological stability. This review aims to summarize and assess the metabolic features, residue status, sample pretreatment methods (solid-phase extraction (SPE), Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS), and some novel pretreatment methods), and detection methods (instrument detection, immunoassay, and some innovative detection methods) for neonicotinoid insecticide residues in food and environmental samples. This review provides detailed references and discussion for the analysis of neonicotinoid insecticide residues, which can effectively promote the establishment of innovative detection methods for neonicotinoid insecticide residues.

Keywords: 5-OH-IMI, 5-hydroxy imidacloprid; 6-CNA, 6-chloronicotinic acid; ACE, Acetamiprid; CLO, Clothianidin; CPF, N-(6-chloro-3-pyridyilmethyl)-N-ethylformamide; CPMA, N-[(6-chloro-3-pyridinyl)methyl]acetamide; CPMF, N-(6-chloro-3-pyridilmethylpyridylmethyl)-N-ethyl-N-methylformamidine; CYC, Cycloxaprid; DIN, Dinotefuran; DN, 1-methyl-3-(tetrahydro-3-furylmethyl) guanidium dihydrogen; Detection technology; FLO, Flonicamid; FLU, Flupyradifurone; GUA, Guadipyr; IMI, Imidacloprid; IMI-guanidine, Imidacloprid guanidine/Desnitro imidacloprid; IMI-guanidine-olefin, Imidacloprid guanidine olefin; IMI-olefin, Imidacloprid olefin; IMI-urea, Imidacloprid-urea; IMID, Imidaclothiz; MNG, 1-Methyl-3 nitroguanidine; Metabolism; N-dm-ACE, N-desmethyl-acetamiprid; NIT, Nitenpyram; Neonicotinoid insecticides; PCD, Paichongding; Residue status; SUL, Sulfoxaflor; Sample preparation; TFNA, 4-trifluoromethylnicotinic acid; THI, Thiacloprid; THIAC, Thiaclocrid amide; THX, Thiamethoxam; TZMU, N-(2-chloro-1, 3-thiazole-5-ylmethyl)-N-methylurea; UF, 1-methyl-3-(tetrahydro-3-furylmethyl) urea.

Publication types

Review