Regulatory effects of marine polysaccharides on gut microbiota dysbiosis: A review

Jieying Ou; Zhuo Wang; Xiaofei Liu; Bingbing Song; Jianping Chen; Rui Li; Xuejing Jia; Riming Huang; Wenzhou Xiang; Saiyi Zhong

doi:10.1016/j.fochx.2022.100444

Regulatory effects of marine polysaccharides on gut microbiota dysbiosis: A review

Food Chem X. 2022 Sep 9:15:100444. doi: 10.1016/j.fochx.2022.100444. eCollection 2022 Oct 30.

Authors

Jieying Ou¹, Zhuo Wang¹, Xiaofei Liu¹, Bingbing Song¹, Jianping Chen¹, Rui Li¹, Xuejing Jia¹, Riming Huang², Wenzhou Xiang³, Saiyi Zhong^{1

4

5}

Affiliations

¹ College of Food Science and Technology, Guangdong Ocean University, Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, Guangdong Province Engineering Laboratory for Marine Biological Products, Guangdong Provincial Engineering Technology Research Center of Seafood, Guangdong Provincial Science and Technology Innovation Center for Subtropical Fruit and Vegetable Processing, Zhanjiang 524088, China.
² College of Food Science, South China Agricultural University, Guangzhou 510642, China.
³ South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
⁴ Shenzhen Research Institute, Guangdong Ocean University, Shenzhen 518108, China.
⁵ Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian 116034, China.

Abstract

The gut microbiota dysbiosis is a state which the physiological combinations of flora are transformed into pathological combinations caused by factors such as diets, pollution, and drugs. Increasing evidence shows that dysbiosis is closely related to many diseases. With the continuous development and utilization of marine resources, marine polysaccharides have been found to regulate dysbiosis in many studies. In this review, we introduce the types of dysbiosis and the degree of it caused by different factors. We highlight the regulating effects of marine polysaccharides on dysbiosis as a potential prebiotic. The mechanisms of marine polysaccharides to regulate dysbiosis including protection of intestinal barrier, regulatory effect on gut microbiota, alteration for related metabolites, and some other possible mechanisms were summarized. And we aim to provide some references for the high-value utilization of marine polysaccharides and new targets for the treatment of gut microbiota dysbiosis by this review.

Keywords: Dysbiosis; Gut microbiota; Marine polysaccharides; Prebiotic; Regulatory effects.

Publication types

Review