Hemodynamic Assessment in Heart Failure with Preserved Ejection Fraction

Kazunori Omote; Steven Hsu; Barry A Borlaug

doi:10.1016/j.ccl.2022.06.010

Hemodynamic Assessment in Heart Failure with Preserved Ejection Fraction

Cardiol Clin. 2022 Nov;40(4):459-472. doi: 10.1016/j.ccl.2022.06.010.

Authors

Kazunori Omote¹, Steven Hsu², Barry A Borlaug³

Affiliations

¹ Department of Cardiovascular Medicine, Mayo Clinic and Foundation, 200 First Street Southwest, Rochester, MN 55905, USA.
² Division of Cardiology, Department of Medicine, Johns Hopkins University, 700 Rutland Avenue, Baltimore, MD 21205, USA.
³ Department of Cardiovascular Medicine, Mayo Clinic and Foundation, 200 First Street Southwest, Rochester, MN 55905, USA. Electronic address: borlaug.barry@mayo.edu.

PMID: 36210131
DOI: 10.1016/j.ccl.2022.06.010

Abstract

Heart failure (HF) with preserved ejection fraction (HFpEF) is characterized by an inability of the heart to perfuse the body without pathologic increases in filling pressure at rest or during exertion. Right heart catheterization provides direct assessment for HF, providing the most robust and direct method to evaluate the central hemodynamic abnormalities, and serves as the gold standard to confirm or refute the presence of HFpEF. This article reviews current understanding of the best practices in the performance and interpretation of hemodynamic assessment, relates important pathophysiologic concepts to clinical care, and discusses current and evidence-based applications of hemodynamics in HFpEF.

Keywords: Cardiac output; Echocardiography; HFpEF; Heart failure.

Publication types

Review

MeSH terms

Cardiac Catheterization
Heart Failure* / diagnosis
Hemodynamics
Humans
Stroke Volume / physiology
Ventricular Function, Left / physiology

Grants and funding

K23 HL146889/HL/NHLBI NIH HHS/United States