The electrodynamics of rod-like microparticles based on optically induced dielectrophoresis

Electrophoresis. 2022 Nov;43(21-22):2175-2183. doi: 10.1002/elps.202200102. Epub 2022 Oct 9.

Abstract

Due to its characteristics of noncontact, non-damage, high flux, and easy-to-achieve flexible manipulation, optically induced dielectrophoresis (ODEP) technology has been employed to manipulate microspherical biological particles, including separation, enrichment, capture, arrangement, and fusion. However, in nature, biomolecules are morphologically diverse, and some of them are rodlike. In order to illustrate the electrodynamics of rodlike particles under the action of ODEP, a transient multi-physical field coupling model of ODEP chip under the hypothesis of electrical double layer thin layer was established in this paper. The arbitrary Lagrangian-Eulerian method is used to track single-rod particle in the strong coupled flow field and electric field simultaneously. The influence of several key factors, including the applied alternating current (AC) electric voltage, the width of optical bright area, and the initial position of particle, on the trajectory of particle center was analyzed in positive dielectrophoresis (DEP) action and negative DEP action, respectively. Especially, the planar motion process of rodlike particles was discussed together. The research results reveal the electrodynamics behavior of rodlike particles based on the action of ODEP, which may provide theoretical support for the further design of rodlike biological cells manipulation chip based on AC ODEP technology in the future.

Keywords: arbitrary Lagrangian-Eulerian; electrodynamics; microfluidic; optically induced dielectrophoresis; rodlike particles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Electrophoresis* / methods