The evaporation of water nanofilms on a solid surface is a widespread and important process in many fields. Herein, we utilize molecular dynamics simulations to demonstrate that the evaporation of a water nanofilm is regulated by applying an alternating electric field (AEF). An AEF at a specific frequency can be resonantly absorbed by the water film. Consequently, the AEF with sufficient strength significantly increases the evaporation rate of the water film (R). In contrast, an AEF of a different frequency and polarization direction decreases R sharply, which is closely related to the strengthened hydrogen bond network and the reduced kinetic energy of the outermost water of the water film. When the maximum amplitude of the AEFs is 0.9 V/nm, which is achievable in a laboratory setting, R spans six orders of magnitude. The effects of applying the AEFs are quite distinct from those of changing the temperature. Notably, the polarization direction of the AEF plays an important role in the water evaporation. To the best of our knowledge, this is the first report on regulating the evaporation rate of a water film, showing that it is possible to use AEFs to tune the properties of nanoscaled water, such as the wettability.