Dynamic changes in host immune system and gut microbiota are associated with the production of SARS-CoV-2 antibodies

Maozhen Han; Yixuan Huang; Hongya Gui; Yixuan Xiao; Maozhang He; Jiling Liu; Xiujing Cao; Meijuan Zheng; Min Lu; Weihua Jia; Hui Li; Xiaoyan Wang; Na Zhang; Shu-An Kong; Xiaohui Liu; Yonggui Wu; Fengchang Wu; Shenghai Huang

doi:10.1136/gutjnl-2022-327561

Dynamic changes in host immune system and gut microbiota are associated with the production of SARS-CoV-2 antibodies

Gut. 2023 Oct;72(10):1996-1999. doi: 10.1136/gutjnl-2022-327561. Epub 2022 Oct 7.

Authors

Maozhen Han^#¹, Yixuan Huang^#², Hongya Gui^#³, Yixuan Xiao^#³, Maozhang He³, Jiling Liu³, Xiujing Cao⁴, Meijuan Zheng⁵, Min Lu⁵, Weihua Jia¹, Hui Li⁶, Xiaoyan Wang⁷, Na Zhang¹, Shu-An Kong², Xiaohui Liu⁸, Yonggui Wu⁹, Fengchang Wu¹⁰, Shenghai Huang^{11

3}

Affiliations

¹ School of Life Sciences, Anhui Medical University, Hefei, Anhui, China.
² Department of Clinical Medicine, The First School of Clinical Medicine, Anhui Medical University, Hefei, Anhui, China.
³ Department of Microbiology, The Key Laboratory of Microbiology and Parasitology of Anhui Province, The Key Laboratory of Zoonoses of High Institutions in Anhui, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
⁴ Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
⁵ Department of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
⁶ Hefei City Maternal and Child Health & Family Planning Service Center, Hefei, Anhui, China.
⁷ Department of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
⁸ State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing, China.
⁹ Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China huangshh68@aliyun.com wufengchang@vip.skleg.cn wuyonggui@medmail.com.cn.
¹⁰ State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing, China huangshh68@aliyun.com wufengchang@vip.skleg.cn wuyonggui@medmail.com.cn.
¹¹ School of Life Sciences, Anhui Medical University, Hefei, Anhui, China huangshh68@aliyun.com wufengchang@vip.skleg.cn wuyonggui@medmail.com.cn.

^# Contributed equally.

No abstract available

Keywords: COVID-19; CYTOKINES; INTESTINAL MICROBIOLOGY; INTESTINAL TRACT.

Publication types

Letter
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Antibodies, Viral
COVID-19*
Gastrointestinal Microbiome*
Gastrointestinal Tract
Humans
Immune System
SARS-CoV-2

Substances

Antibodies, Viral