Glia-neuron interplay drives circadian glycosphingolipid homeostasis and structural brain plasticity

Abstract

Glia-neuronal interplay is critical for circadian regulation of physiology and behavior. In this issue of Neuron, Vaughen et al. identify daily variations of glycosphingolipids that depend on glia and whose disruption alters proteostasis and daily structural plasticity of Drosophila circadian circuits.