Transcriptome analysis reveals the molecular regulatory network of muscle development and meat quality in Sunit lamb supplemented with dietary probiotic

Min Zhang; Yueying Guo; Rina Su; Mirco Corazzin; Ran Hou; Jingyu Xie; Yue Zhang; Lihua Zhao; Lin Su; Ye Jin

doi:10.1016/j.meatsci.2022.108996

Transcriptome analysis reveals the molecular regulatory network of muscle development and meat quality in Sunit lamb supplemented with dietary probiotic

Meat Sci. 2022 Dec:194:108996. doi: 10.1016/j.meatsci.2022.108996. Epub 2022 Sep 28.

Authors

Min Zhang¹, Yueying Guo¹, Rina Su², Mirco Corazzin³, Ran Hou¹, Jingyu Xie¹, Yue Zhang¹, Lihua Zhao¹, Lin Su¹, Ye Jin⁴

Affiliations

¹ College of Food Science and Engineering, Inner Mongolia Agriculture University, China.
² Inner Mongolia Vocational College of Chemical Engineering, China.
³ Department of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Italy.
⁴ College of Food Science and Engineering, Inner Mongolia Agriculture University, China. Electronic address: jinyeyc@sohu.com.

PMID: 36195032
DOI: 10.1016/j.meatsci.2022.108996

Abstract

Supplementing animal feed with probiotic additives can promote muscle production and improve meat quality. The study aimed to explore the effects of dietary probiotics supplementation on the performance, meat quality and muscle transcriptome profile in Sunit lamb. Overall, feeding probiotics significantly increased the body length, LT area, pH_24h and intramuscular fat (IMF) content, but decreased cooking loss and meat shear force compared to the control group (P < .05). A total of 651 differentially expressed genes (DEGs) were found in probiotic supplemented lambs. Pathway analysis revealed that DEGs were involved in multiple pathways related to muscle development and fat deposition, such as the ECM-receptor interactions, the MAPK signaling pathway and the FoxO signaling pathway. Therefore, dietary probiotic supplementation can improve muscle development and final meat quality in Sunit lambs by altering gene expression profiles associated with key pathways, providing unique insights into the molecular mechanisms by which dietary probiotics regulate muscle development in the lamb industry.

Keywords: Dietary probiotics; Intramuscular fat deposition; Meat quality; Muscle development; Sunit lamb.

MeSH terms

Animal Feed / analysis
Animals
Dietary Supplements*
Gene Expression Profiling / veterinary
Meat / analysis
Muscle Development
Probiotics* / pharmacology
Sheep
Sheep, Domestic
Transcriptome