Transfixing Anterior Laryngeal Cleft in a Malformed Stillborn at Term: Case Report

Fetal Pediatr Pathol. 2023 Jun;42(3):479-482. doi: 10.1080/15513815.2022.2128950. Epub 2022 Oct 3.

Abstract

Introduction: Laryngeal clefts (LC) are upper respiratory malformations predominately found in the posterior laryngeal wall. The frequency is 1:10,000, more frequently affect males, and can be syndromic features. There is no report of a transfixing anterior laryngeal cleft. Case report: This diabetic mother at full-term pregnancy delivered a stillborn macrosomic 4780 g dysmorphic stillborn male with left renal agenesis, aortic coarctation, and anterior laryngeal cleft. Conclusion: Anterior laryngeal clefts can occur, and in this case, occurred in association with renal agenesis and maternal diabetes.

Keywords: Larynx cleft; diabetes mellitus; laryngeal malformation; laryngotracheal anomalies; pediatric otolaryngology.

Publication types

  • Case Reports

MeSH terms

  • Congenital Abnormalities*
  • Female
  • Humans
  • Larynx* / abnormalities
  • Male
  • Pregnancy
  • Stillbirth

Supplementary concepts

  • Laryngeal cleft
  • Hereditary renal agenesis
  • Renal Adysplasia