Airborne spores' dissemination of a swine associated Clostridioides difficile clone

Frederico Alves; Manuela Cano; Greice Brondani; Alexandra Nunes; Mónica Oleastro

doi:10.1016/j.anaerobe.2022.102651

Airborne spores' dissemination of a swine associated Clostridioides difficile clone

Anaerobe. 2022 Dec:78:102651. doi: 10.1016/j.anaerobe.2022.102651. Epub 2022 Sep 29.

Authors

Frederico Alves¹, Manuela Cano², Greice Brondani¹, Alexandra Nunes³, Mónica Oleastro⁴

Affiliations

¹ Infectious Diseases Department, National Institute of Health Dr Ricardo Jorge (INSA), Lisbon, Portugal.
² Environmental Health Department, National Institute of Health Dr Ricardo Jorge (INSA), Lisbon, Portugal.
³ Infectious Diseases Department, National Institute of Health Dr Ricardo Jorge (INSA), Lisbon, Portugal; Faculty of Veterinary Medicine, Lusófona University, Lisbon, Portugal.
⁴ Infectious Diseases Department, National Institute of Health Dr Ricardo Jorge (INSA), Lisbon, Portugal. Electronic address: monica.oleastro@insa.min-saude.pt.

PMID: 36184011
DOI: 10.1016/j.anaerobe.2022.102651

Abstract

This study supports the airborne dissemination of Clostridioides difficile spores. Of the sieve impaction samples collected at a swine production unit, 66.7% were positive and all belonged to the predominantly established clone. Spores' density varied according to the characteristics of the animal population, suggesting the possibility of airborne transmission.

MeSH terms

Animals
Clone Cells
Clostridioides
Clostridioides difficile* / genetics
Spores, Bacterial
Swine