We present a case of diffuse uterine leiomyomatosis in a 38-year-old nulliparous female presenting with abdominal distension and infertility, which is very rarely reported and commonly misdiagnosed. Magnetic resonance imaging (MRI) of the abdomen and pelvis showed an enlarged uterus of size 25 × 20 ×13 cm with a few fibroids in the lower uterine segment and pressure effects on the ureter, causing hydroureteronephrosis. The fundal region and upper uterine segment were extensively thickened with a mildly thinned-out junctional zone. A total abdominal hysterectomy was performed, and the diagnosis of diffuse leiomyomatosis of the uterus was confirmed on histopathological examination. The post-operative period was complicated by hypovolemic shock, which was managed by transfusion of multiple units of blood, blood components, and hemostatics. On the ninth post-operative day, the patient gained full recovery and was discharged.
Keywords: diffuse uterine leiomyomatosis; dul; leiomyomatosis; surgical management; uterine leiomyomatosis.
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