High-level dolutegravir resistance can emerge rapidly from few variants and spread by recombination: implications for INSTI salvage therapy

MeSH terms

• Drug Resistance, Viral
• HIV Infections* / drug therapy
• HIV Integrase Inhibitors* / pharmacology
• HIV Integrase Inhibitors* / therapeutic use
• Heterocyclic Compounds, 3-Ring / pharmacology
• Heterocyclic Compounds, 3-Ring / therapeutic use
• Humans
• Oxazines
• Piperazines
• Pyridones / therapeutic use
• Recombination, Genetic
• Salvage Therapy