Negative affectivity and disinhibition as moderators of an interpersonal pathway to suicidal behavior in borderline personality disorder

Clin Psychol Sci. 2022 Sep;10(5):856-868. doi: 10.1177/21677026211056686. Epub 2022 Jan 3.

Abstract

This longitudinal study examined whether personality traits moderate the link between interpersonal dysfunction and suicidal behavior in a high-risk sample of 458 individuals diagnosed with borderline personality disorder (BPD). Participants were assessed annually for up to 30 years (mean number of follow-ups = 7.82). Using multilevel structural equation modeling, we examined i) longitudinal, within-person relationships among interpersonal dysfunction, suicidal ideation, and suicide attempts; and ii) moderation of these relationships by negative affectivity and disinhibition. Negative affectivity predicted a stronger within-person coupling between interpersonal dysfunction and suicidal ideation. Disinhibition predicted a stronger coupling between ideation and suicide attempts. Assessing negative affectivity and disinhibition in a treatment setting may guide clinician vigilance toward those at highest risk for interpersonally triggered suicidal behaviors.

Keywords: borderline personality disorder; disinhibition; interpersonal; negative affectivity; suicide.