In this article, an improved model-free adaptive control (iMFAC) is proposed for discrete-time multi-input multioutput (MIMO) nonlinear systems with an event-triggered transmission scheme and quantization (ETQ). First, an event-triggered scheme is designed, and the structure of the uniform quantizer with an encoding-decoding mechanism is given. With the concept of partial form dynamic linearization based on event-triggered and quantization (PFDL-ETQ), a linearized data model of the MIMO nonlinear system is constructed. Then, an improved model-free adaptive controller with the ETQ process is designed. By this design, the update of the pseudo partitioned Jacobean matrix (PPJM) estimates and control inputs occurs only when the trigger conditions are met, which reduces the network transmission burden and saves the computing resources. Theoretical analysis shows that the proposed iMFAC with the ETQ process can achieve a bounded convergence of tracking error. Finally, a numerical simulation and a biaxial gantry motor contour tracking control system simulation are given to illustrate the feasibility of the proposed iMFAC method with the ETQ process.