Pityriasis Rubra Pilaris Transcriptomics Implicate T Helper 17 Signaling and Correlate with Response to Ixekizumab, with Distinct Gene Expression Profiles in Nonresponders

J Invest Dermatol. 2023 Mar;143(3):501-504.e1. doi: 10.1016/j.jid.2022.09.005. Epub 2022 Sep 24.

Authors

Dylan Haynes¹, Taylor Reiter², Rose Velasco¹, Matthew Chang¹, Rajan Kulkarni¹, Gail Kent¹, Jennifer Strunck¹, Pamela Cassidy¹, Teri M Greiling³

Affiliations

¹ Department of Dermatology, Oregon Health & Science University, Portland, Oregon, USA.
² Center for Health AI, University of Colorado School of Medicine, Aurora, Colorado, USA; Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, USA.
³ Department of Dermatology, Oregon Health & Science University, Portland, Oregon, USA. Electronic address: Greiling@ohsu.edu.

PMID: 36167251
DOI: 10.1016/j.jid.2022.09.005

No abstract available

Publication types

Research Support, N.I.H., Extramural
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Monoclonal, Humanized
Gene Expression Profiling
Humans
Pityriasis Rubra Pilaris*
Transcriptome

Substances

ixekizumab
Antibodies, Monoclonal, Humanized