IgG4 paratesticular fibrous pseudotumor: Case presentation and literature review

Layla Zeitouni; Faiz Motiwala; Neelakshi Goyal; Emma Watura; Waseem Mulhem; Mohamed Y Hammadeh

doi:10.1016/j.eucr.2022.102213

IgG4 paratesticular fibrous pseudotumor: Case presentation and literature review

Urol Case Rep. 2022 Sep 17:45:102213. doi: 10.1016/j.eucr.2022.102213. eCollection 2022 Nov.

Authors

Layla Zeitouni¹, Faiz Motiwala², Neelakshi Goyal³, Emma Watura⁴, Waseem Mulhem², Mohamed Y Hammadeh²

Affiliations

¹ Queen Elizabeth University Hospital, Glasgow, Scotland, UK.
² Urology Department, Lewisham and Greenwich NHS Trust, London, UK.
³ Histopathology Department, Lewisham and Greenwich NHS Trust, London, UK.
⁴ Radiology Department, Lewisham and Greenwich NHS Trust, London, UK.

Abstract

PFP with IgG-4 immunostaining is a rare paratesticular tumour. Pre-operative ultrasound scan and MRI usually confirm the benign nature of the paratesticular mass avoiding the need for radical orchiectomy. The final diagnosis is based on histology of the removed paratesticular tumour. FDG PET scan plays an important role in ruling out systematic IgG4-related disease (IgG4-RD). We describe a case of multiple paratesticular fibrous pseudotumors with IgG4 immunostaining, not associated with systemic IgG4 related disease.

Keywords: IgG4 fibrous pseudotumor; IgG4-RD, IgG4- related diseases; PFP, paratesticular fibrous pseudotumour; Paratesticular tumour; Scrotal tumour.

Publication types

Case Reports