Probiotics with anti-type 2 diabetes mellitus properties: targets of polysaccharides from traditional Chinese medicine

Chin J Nat Med. 2022 Sep;20(9):641-655. doi: 10.1016/S1875-5364(22)60210-3.

Abstract

Traditional Chinese medicine polysaccharides is a biologically active ingredient that is not easy to be digested. It is fermented by intestinal microflora to promote qualitative and selective changes in the composition of the intestinal microbiome, which often result in beneficial effects on the health of the host. People call it "prebiotics". In this review, we systematically summarized the anti-diabetic effect of traditional Chinese medicine polysaccharides. These polysaccharides regulate the metabolism of sugar and lipids by inter-influence with the intestinal microflora, and maintain human health, while improving type 2 diabetes-like symptoms such as high blood glucose, and abnormal glucose and lipid metabolism.

Keywords: Intestinal microflora; Prebiotics; Traditional Chinese medicine polysaccharide; Type 2 diabetes mellitus.

Publication types

  • Review

MeSH terms

  • Blood Glucose / metabolism
  • Diabetes Mellitus, Type 2* / drug therapy
  • Diabetes Mellitus, Type 2* / metabolism
  • Humans
  • Lipids
  • Medicine, Chinese Traditional
  • Polysaccharides / pharmacology
  • Probiotics* / therapeutic use

Substances

  • Blood Glucose
  • Lipids
  • Polysaccharides