Analysis of MSCs' secretome and EVs cargo: Evaluation of functions and applications

Valentina Urrata; Marco Trapani; Mara Franza; Francesco Moschella; Anna Barbara Di Stefano; Francesca Toia

doi:10.1016/j.lfs.2022.120990

Analysis of MSCs' secretome and EVs cargo: Evaluation of functions and applications

Life Sci. 2022 Nov 1:308:120990. doi: 10.1016/j.lfs.2022.120990. Epub 2022 Sep 22.

Authors

Valentina Urrata¹, Marco Trapani², Mara Franza³, Francesco Moschella¹, Anna Barbara Di Stefano⁴, Francesca Toia⁵

Affiliations

¹ BIOPLAST-Laboratory of BIOlogy and Regenerative Medicine-PLASTic Surgery, Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127 Palermo, Italy.
² BIOPLAST-Laboratory of BIOlogy and Regenerative Medicine-PLASTic Surgery, Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127 Palermo, Italy; Plastic and Reconstructive Surgery, Department of Oncology, Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone", 90127 Palermo, Italy.
³ Plastic and Reconstructive Surgery, Department of Oncology, Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone", 90127 Palermo, Italy; Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127 Palermo, Italy.
⁴ BIOPLAST-Laboratory of BIOlogy and Regenerative Medicine-PLASTic Surgery, Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127 Palermo, Italy. Electronic address: annabarbara.distefano@unipa.it.
⁵ BIOPLAST-Laboratory of BIOlogy and Regenerative Medicine-PLASTic Surgery, Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127 Palermo, Italy; Plastic and Reconstructive Surgery, Department of Oncology, Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone", 90127 Palermo, Italy; Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127 Palermo, Italy.

PMID: 36155182
DOI: 10.1016/j.lfs.2022.120990

No abstract available

Keywords: 3D cultures; Epigenetic; Extracellular vesicles; Mesenchymal stem cells; Secretome; miRNAs.

Publication types

Review

MeSH terms

Extracellular Vesicles* / metabolism
Mesenchymal Stem Cell Transplantation*
Secretome