Mucopedia 101: capturing and assigning mucin-domain glycoproteins

Abigail E Reeves; Mia L Huang

doi:10.1016/j.tim.2022.09.004

Mucopedia 101: capturing and assigning mucin-domain glycoproteins

Trends Microbiol. 2023 May;31(5):428-429. doi: 10.1016/j.tim.2022.09.004. Epub 2022 Sep 21.

Authors

Abigail E Reeves¹, Mia L Huang²

Affiliations

¹ Department of Molecular Medicine, Scripps Research, 10550 N. Torrey Pines Rd, La Jolla, CA 92037, USA; Skaggs Graduate School of Chemical and Biological Sciences, Scripps Research, 10550 N. Torrey Pines Rd, La Jolla, CA 92037, USA.
² Department of Molecular Medicine, Scripps Research, 10550 N. Torrey Pines Rd, La Jolla, CA 92037, USA. Electronic address: miahuang@scripps.edu.

PMID: 36153262
DOI: 10.1016/j.tim.2022.09.004

Abstract

Glycoproteins bearing mucin domains serve important biological functions, yet they are understudied due to their dense glycosylation. Malaker et al. describe a new tool that will advance the capture, identification, and prediction of new members of the 'mucinome'.

Publication types

Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural

MeSH terms

Glycoproteins*
Glycosylation
Mucins* / metabolism

Substances

Mucins
Glycoproteins

Grants and funding

R35 GM142462/GM/NIGMS NIH HHS/United States