1 Steven G. DuBois, MD, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA; Abha A. Gupta, MD, Department of Paediatrics, Hospital for Sick Children and Princess Margaret Cancer Center, University of Toronto, Toronto, Canada; and Emanuela Palmerini, MD, Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies Unit, IRCCS Istituto Ortopedico Rizzoli and Bologna University, Bologna, Italy.