Pathogen evolution during vaccination campaigns

Troy Day; David A Kennedy; Andrew F Read; Sylvain Gandon

doi:10.1371/journal.pbio.3001804

Pathogen evolution during vaccination campaigns

PLoS Biol. 2022 Sep 23;20(9):e3001804. doi: 10.1371/journal.pbio.3001804. eCollection 2022 Sep.

Authors

Troy Day¹, David A Kennedy², Andrew F Read^{2

3}, Sylvain Gandon⁴

Affiliations

¹ Department of Mathematics and Statistics, Department of Biology, Queen's University, Kingston, Ontario, Canada.
² Department of Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America.
³ Department of Entomology, Pennsylvania State University, University Park, Pennsylvania, United States of America.
⁴ CEFE, CNRS, Univ Montpellier, EPHE, IRD, Montpellier, France.

Abstract

Following the initiation of the unprecedented global vaccination campaign against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), attention has now turned to the potential impact of this large-scale intervention on the evolution of the virus. In this Essay, we summarize what is currently known about pathogen evolution in the context of immune priming (including vaccination) from research on other pathogen species, with an eye towards the future evolution of SARS-CoV-2.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

COVID-19* / prevention & control
Humans
Immunization Programs
SARS-CoV-2*
Vaccination

Abstract

Publication types

MeSH terms

Grants and funding