A cohort study of vitamins contents in human milk from maternal-infant factors

Weicang Qiao; Jingyao Chen; Minghui Zhang; Yaling Wang; Baoyu Yang; Junying Zhao; Tiemin Jiang; Lijun Chen

doi:10.3389/fnut.2022.993066

A cohort study of vitamins contents in human milk from maternal-infant factors

Front Nutr. 2022 Sep 6:9:993066. doi: 10.3389/fnut.2022.993066. eCollection 2022.

Authors

Weicang Qiao^{1

2}, Jingyao Chen^{1

2}, Minghui Zhang^{1

2}, Yaling Wang^{1

2}, Baoyu Yang^{1

2}, Junying Zhao^{1

2

3}, Tiemin Jiang³, Lijun Chen^{1

2

3}

Affiliations

¹ National Engineering Center of Dairy for Maternal and Child Health, Beijing Sanyuan Foods Co. Ltd., Beijing, China.
² Beijing Engineering Research Center of Dairy, Beijing Sanyuan Foods Co. Ltd., Beijing, China.
³ South Asia Branch of National Engineering Center of Dairy for Maternal and Child Health, Guilin University of Technology, Guilin, China.

Abstract

Human milk vitamin content is an important indicator to evaluate the nutritional composition of human milk. This paper investigates the influence of maternal and infant factors on the dynamics of human milk vitamin content. A total of 147 mother-infant pairs from 3 different cities (north-south distribution) in China were selected and 9 major vitamins were measured in 332 human milk samples. The three vitamins (vitamin A, β-carotene, and pantothenic acid) showed significant downward trends with lactation period (| r | > 0.3, p < 0.05). The lactation period factor could explain the negative variation of vitamin A (21.2%) and pantothenic acid (9.5%). The factors of lactation period and oils intake could jointly explain variations of β-carotene (11.8%). (Registration number: NCT02658500).

Keywords: cohort study; dynamics changes; human milk; maternal-infant factors; vitamins.

Associated data

ClinicalTrials.gov/NCT02658500