Indoor Mobility, Frailty, and Disability in Community-Dwelling Older Adults: A Mediation Model

Paolo Riccardo Brustio; Anna Mulasso; Samuel D'Emanuele; Gianluca Zia; Luca Feletti; Susanna Del Signore; Alberto Rainoldi

doi:10.3390/ijerph191811386

Indoor Mobility, Frailty, and Disability in Community-Dwelling Older Adults: A Mediation Model

Int J Environ Res Public Health. 2022 Sep 9;19(18):11386. doi: 10.3390/ijerph191811386.

Authors

Paolo Riccardo Brustio^{1

2

3}, Anna Mulasso^{1

4}, Samuel D'Emanuele², Gianluca Zia⁵, Luca Feletti⁶, Susanna Del Signore⁵, Alberto Rainoldi^{1

4}

Affiliations

¹ NeuroMuscularFunction, Research Group, School of Exercise & Sport Sciences, University of Torino, 10126 Torino, Italy.
² Department of Neuroscience, Biomedicine and Movement, University of Verona, 37124 Verona, Italy.
³ Department of Clinical and Biological Sciences, University of Torino, 10126 Torino, Italy.
⁴ Department of Medical Sciences, University of Torino, 10126 Torino, Italy.
⁵ Bluecompanion Ltd., London NW8 9DD, UK.
⁶ Caretek s.r.l., 10127 Torino, Italy.

Abstract

The general population, but especially older adults, were forced or encouraged to stay home during the recent COVID-19 pandemic. In this context, indoor mobility (IM, the number of steps performed daily at home) may be informative about the general health status of older adults. The present study aimed at evaluating the relationship between IM, frailty (loss of functional reserve including both physical and psychosocial domains), and disability (loss of autonomy measured as activities of daily life, ADLs) in a sample of community-dwelling Italian older adults. Specifically, the primary objective was to investigate IM and disability differences between robust and frail older adults. The secondary objective was to test if frailty is in the causal sequence between IM and disability, i.e., as a mediator in their relationship. Thirty-two participants (mean age = 70 ± 6 years; 56.2% women) were recruited. Frailty and disability were evaluated using the Tilburg Frailty Indicator and the Groningen Activity Restriction Scale, respectively. IM at home was measured via an Adamo wristwatch (a connected accelerometer). One-way analyses of covariance, controlling for age and gender, showed that robust participants, classified according to a score higher than five points in the Tilburg Frailty Indicator, performed significantly more IM (F_1,28 = 4.639; p = 0.04) and presented lower disability grade than frail ones (F_1,28 = 4.342; p =0.046). Only physical frailty was a mediator in the relationship between IM and disability (F_2,29 = 8.538, p < 0.001), with a fully mediated model (z = -2.073, p < 0.04). Conversely, the total frailty score was not a mediator in the same relationship, but with IM accounted for the variance in disability (F_2,29 = 8.538, p < 0.001; R² = 33.7%). Our results suggested that frail older adults restricted their IM more and presented a higher level of disability compared to robust older adults. Moreover, data suggest that IM reduction may have a negative impact on physical frailty and indirectly increase disability.

Keywords: ADL; Adamo; active living; aged population; physical activity; physical frailty; walking.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
COVID-19* / epidemiology
Female
Frail Elderly / psychology
Frailty* / complications
Geriatric Assessment / methods
Humans
Independent Living
Male
Middle Aged
Pandemics

Grants and funding

This work was supported by the Innovative Medicine Initiative (IMI; 9th Call, 2013) with the SPRINTT (Sarcopenia & physical frailty in older people: multi-component treatment strategies) project [grant number 115621]. There was no additional external funding received for this study.