Evaluating the Efficacy and Safety of Different Pterygium Surgeries: A Review of the Literature

Int J Environ Res Public Health. 2022 Sep 9;19(18):11357. doi: 10.3390/ijerph191811357.

Abstract

The search for the "gold standard" in the surgical treatment of pterygium has been ongoing for over two decades. Despite the development of various surgical techniques, recurrence rates range from 6.7% to 88% depending on the method used. This review discusses the latest and most commonly used methods for the surgical removal of pterygium, primarily focusing on efficacy and safety. Moreover, this review includes articles that either evaluated or compared surgical methods and clinical trials for primary and recurrent pterygium. Limited data are available on combined methods as well as on the efficacy of adjuvant treatment. The use of adjuvant intraoperative mitomycin C (MMC) and conjunctival autografting (CAU) are the two most highly recommended options, as they have the lowest rates of postoperative recurrence.

Keywords: amniotic membrane transplantation; conjunctival autograft; limbal-conjunctival autograft; pterygium; pterygium surgery.

Publication types

  • Review

MeSH terms

  • Conjunctiva / abnormalities
  • Conjunctiva / transplantation
  • Follow-Up Studies
  • Humans
  • Mitomycin / therapeutic use
  • Pterygium* / drug therapy
  • Pterygium* / surgery
  • Recurrence
  • Treatment Outcome

Substances

  • Mitomycin

Supplementary concepts

  • Pterygium Of Conjunctiva And Cornea

Grants and funding

This research received no external funding.