Kidney Transplantation during the First Year of COVID-19 Pandemic in Our Center

Arch Esp Urol. 2022 Aug;75(6):559-566. doi: 10.56434/j.arch.esp.urol.20227506.82.

Abstract

Introduction: SARS-CoV2 pandemic has altered the normal activity in our day-to-day life. During the most critical moments of the pandemic at the hospital, attendance and programmed activities had to be reduced to a minimum, including kidney transplants. Hospitals with this kind of activity had to suspend or restructure it due to the decrease in the number of donors with a solid organ donation profile, the lack of knowledge as to whether the disease could be transmitted through transplantation or the risk that was believed to be associated with the admission of patients with end-stage chronic kidney disease or immunosuppressive treatment.

Methods: A retrospective review of all patients who had received a kidney transplant at Doctor Peset University Hospital in Valencia was performed from March 2020 to March 2021. The objective was to study the safety of kidney transplantation and the incidence of COVID-19 disease in kidney transplant patients during this pandemic period.

Results: 56 cases of kidney transplantation were included, most of them male with an average age of 56 years old, and variable comorbidity such as hypertension, dyslipidemia, an average body mass index of 26 and undergoing renal replacement therapy by hemodialysis. Regarding the organ donors, more than 50% were male patients and the donation was in encephalic death. The average cold ischemia time was 15 hours. Postoperative complications were mostly graded I and II in the Clavien-Dindo classification. 5.4% of the recipients had passed the SARS-CoV2 infection prior to the transplant and 5.4% were infected with COVID-19 after the transplant.

Conclusion: In our experience, the current kidney transplant program seems viable and safe, even during periods of health emergencies.

Keywords: COVID-19; SARS-CoV2; kidney transplantation; urology.

MeSH terms

  • COVID-19*
  • Female
  • Humans
  • Kidney Failure, Chronic* / therapy
  • Kidney Transplantation*
  • Male
  • Middle Aged
  • Pandemics
  • RNA, Viral
  • SARS-CoV-2

Substances

  • RNA, Viral