A coagulation factor moonlights in the heart

Science. 2022 Sep 23;377(6613):1382-1383. doi: 10.1126/science.ade2538. Epub 2022 Sep 22.

Abstract

Liver-derived coagulation factor XI protects the heart from failure.

Publication types

  • Comment

MeSH terms

  • Animals
  • Bone Morphogenetic Protein 7* / metabolism
  • Factor XI* / metabolism
  • Heart Failure* / metabolism
  • Humans
  • Liver Diseases* / complications
  • Liver Diseases* / enzymology
  • Liver* / metabolism
  • Mice
  • Myocardium* / metabolism

Substances

  • Bone Morphogenetic Protein 7
  • Factor XI