Comparison of Convolutional Neural Networks and Transformers for the Classification of Images of COVID-19, Pneumonia and Healthy Individuals as Observed with Computed Tomography

Abstract

In this work, the performance of five deep learning architectures in classifying COVID-19 in a multi-class set-up is evaluated. The classifiers were built on pretrained ResNet-50, ResNet-50r (with kernel size 5×5 in the first convolutional layer), DenseNet-121, MobileNet-v3 and the state-of-the-art CaiT-24-XXS-224 (CaiT) transformer. The cross entropy and weighted cross entropy were minimised with Adam and AdamW. In total, 20 experiments were conducted with 10 repetitions and obtained the following metrics: accuracy (Acc), balanced accuracy (BA), F₁ and F₂ from the general Fβ macro score, Matthew's Correlation Coefficient (MCC), sensitivity (Sens) and specificity (Spec) followed by bootstrapping. The performance of the classifiers was compared by using the Friedman-Nemenyi test. The results show that less complex architectures such as ResNet-50, ResNet-50r and DenseNet-121 were able to achieve better generalization with rankings of 1.53, 1.71 and 3.05 for the Matthew Correlation Coefficient, respectively, while MobileNet-v3 and CaiT obtained rankings of 3.72 and 5.0, respectively.

Keywords: COVID-19; Friedman–Nemenyi tests; bootstrap; deep neural networks; transformer; weighted cross entropy.