Clinical application of transcranial magnetic stimulation in multiple sclerosis

Xiaoliang Zhou; Kailin Li; Si Chen; Wenbin Zhou; Jing Li; Qing Huang; Tingting Xu; Zhiyuan Gao; Dongyu Wang; Shuo Zhao; Hao Dong

doi:10.3389/fimmu.2022.902658

Clinical application of transcranial magnetic stimulation in multiple sclerosis

Front Immunol. 2022 Sep 5:13:902658. doi: 10.3389/fimmu.2022.902658. eCollection 2022.

Authors

Xiaoliang Zhou^{1

2}, Kailin Li^{1

3}, Si Chen^{1

2}, Wenbin Zhou^{1

2}, Jing Li^{1

2}, Qing Huang^{1

2}, Tingting Xu³, Zhiyuan Gao³, Dongyu Wang³, Shuo Zhao³, Hao Dong³

Affiliations

¹ Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.
² National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
³ Xiangya School of Medicine, Central South University, Changsha, China.

Abstract

Multiple sclerosis (MS) is a common chronic, autoimmune-mediated inflammatory and neurodegenerative disease of the central nervous system. The treatment of MS has enormous progress with disease-modifying drugs, but the complexity of the disease course and the clinical symptoms of MS requires personalized treatment and disease management, including non-pharmacological treatment. Transcranial magnetic stimulation (TMS) is a painless and non-invasive brain stimulation technique, which has been widely used in neurological diseases. In this review, we mainly focus on the progress of physiological assessment and treatment of TMS in MS.

Keywords: demyelinating disease of the central nervous system; multiple sclerosis; non-invasive brain stimulation; theta burst stimulation; transcranial magnetic stimulation.

Publication types

Review

MeSH terms

Brain
Humans
Multiple Sclerosis* / diagnosis
Multiple Sclerosis* / therapy
Neurodegenerative Diseases*
Transcranial Magnetic Stimulation / methods