Highly efficient base editing in rabbit by using near-PAMless engineered CRISPR/Cas9 variants

Sci China Life Sci. 2023 Mar;66(3):635-638. doi: 10.1007/s11427-021-2165-1. Epub 2022 Sep 16.

Authors

Zhongtian Zhang^#¹, Xinyu Wu^#¹, Jie Yang¹, Xin Liu¹, Ruonan Liu¹, Yuning Song²

Affiliations

¹ Jilin Provincial Key Laboratory of Animal Embryo Engineering, College of Veterinary Medicine, Jilin University, Changchun, 130062, China.
² Jilin Provincial Key Laboratory of Animal Embryo Engineering, College of Veterinary Medicine, Jilin University, Changchun, 130062, China. songyuning0313@jlu.edu.cn.

^# Contributed equally.

PMID: 36125667
DOI: 10.1007/s11427-021-2165-1

No abstract available

Publication types

Letter

MeSH terms

Animals
CRISPR-Associated Protein 9 / genetics
CRISPR-Cas Systems* / genetics
Gene Editing*
RNA, Guide, CRISPR-Cas Systems
Rabbits

Substances

CRISPR-Associated Protein 9
RNA, Guide, CRISPR-Cas Systems