Use of oral chemotherapeutic agent, chlorambucil, as palliative treatment of thryoid adenocarcinoma in a golden-headed lion tamarin (Leontopithecus chrysomelas)

J Med Primatol. 2023 Feb;52(1):79-82. doi: 10.1111/jmp.12620. Epub 2022 Sep 20.

Abstract

This case report describes the use of chlorambucil in a 7.5-year-old golden-headed lion tamarin (Leontopithecus chrysomelas) as palliative therapy for thyroid adenocarcinoma. Treatment was initiated at 0.1 mg/kg orally once daily. No physical abnormalities or substantial changes in complete blood cell counts and thyroid hormone levels from serial samples were detected.

Keywords: callitrichid; chlorambucil; immunosuppressant; neoplasm; non-human primate.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Chlorambucil / therapeutic use
  • Leontopithecus*
  • Palliative Care

Substances

  • Chlorambucil

Supplementary concepts

  • Leontopithecus rosalia