Identification and Treatment of Acute Pelvic Inflammatory Disease and Associated Sequelae

Obstet Gynecol Clin North Am. 2022 Sep;49(3):551-579. doi: 10.1016/j.ogc.2022.02.019.

Abstract

Pelvic inflammatory disease (PID) is an ascending polymicrobial infection of the upper female genital tract. The presentation of PID varies from asymptomatic cases to severe sepsis. The diagnosis of PID is often one of exclusion. Primary treatment for PID includes broad-spectrum antibiotics with coverage against gonorrhea, chlamydia, and common anaerobic and aerobic bacteria. If not clinically improved by antibiotics, percutaneous drain placement can promote efficient source control, as is often the case with large tubo-ovarian abscesses. Ultimately, even with treatment, PID can result in long-term morbidity, including chronic pelvic pain, infertility, and ectopic pregnancy.

Keywords: Acute pelvic pain; Pelvic inflammatory disease (PID); Sexually transmitted infection (STI); Tubo-ovarian abscess (TOA).

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Disease Progression
  • Female
  • Humans
  • Pelvic Inflammatory Disease* / diagnosis
  • Pelvic Inflammatory Disease* / microbiology
  • Pelvic Inflammatory Disease* / therapy
  • Pregnancy
  • Pregnancy, Ectopic* / diagnosis
  • Pregnancy, Ectopic* / therapy

Substances

  • Anti-Bacterial Agents