Obstetric Disorders and Critical Illness

Clin Chest Med. 2022 Sep;43(3):471-488. doi: 10.1016/j.ccm.2022.04.008.

Abstract

In this article, we discuss some of the more common obstetric-related conditions that can lead to critical illness and require management in an ICU. These include the hypertensive disorders of pregnancy, postpartum hemorrhage, hemolysis, elevated liver enzymes, and low platelet syndrome, acute fatty liver of pregnancy, amniotic fluid embolism, and peripartum cardiomyopathy. We also discuss pulmonary embolism and Covid-19. Despite not being specific to obstetric patients, pulmonary embolism is a common, life-threatening diagnosis in pregnancy with particular risks and management aspects. Covid-19 does not seem to occur with higher frequency in pregnant women, but it leads to higher rates of ICU admissions and mechanical ventilation in pregnant women than in their nonpregnant peers. Its prevalence during our current global pandemic makes it important to discuss in this article. We provide a basis for critical care physicians to be engaged in informed conversations and management in a multidisciplinary manner with other relevant providers in the care of critically ill pregnant and postpartum women.

Keywords: Acute fatty liver of pregnancy; Amniotic fluid embolism; HELLP syndrome; Hypertensive disorders of pregnancy; Obstetric critical care; Peripartum cardiomyopathy; Postpartum hemorrhage; Pulmonary embolism.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • COVID-19*
  • Critical Illness / therapy
  • Female
  • Humans
  • Intensive Care Units
  • Pregnancy
  • Pregnancy Complications* / diagnosis
  • Pregnancy Complications* / epidemiology
  • Pregnancy Complications* / therapy
  • Pulmonary Embolism*