OPDA, more than just a jasmonate precursor

Guillermo H Jimenez Aleman; Venkatesh P Thirumalaikumar; Georg Jander; Alisdair R Fernie; Aleksandra Skirycz

doi:10.1016/j.phytochem.2022.113432

OPDA, more than just a jasmonate precursor

Phytochemistry. 2022 Dec:204:113432. doi: 10.1016/j.phytochem.2022.113432. Epub 2022 Sep 14.

Authors

Guillermo H Jimenez Aleman¹, Venkatesh P Thirumalaikumar¹, Georg Jander¹, Alisdair R Fernie², Aleksandra Skirycz³

Affiliations

¹ Boyce Thompson Institute, Ithaca, NY, 14853, USA.
² Max Planck Institute of Molecular Plant Physiology, 14476, Potsdam, Germany. Electronic address: fernie@mpimp-golm.mpg.de.
³ Boyce Thompson Institute, Ithaca, NY, 14853, USA. Electronic address: as4258@cornell.edu.

PMID: 36115386
DOI: 10.1016/j.phytochem.2022.113432

Abstract

The oxylipin 12-oxo-phytodienoic acid (OPDA) is known as a biosynthetic precursor of the important plant hormone jasmonic acid. However, OPDA is also a signaling molecule with functions independent of jasmonates. OPDA involvement in diverse biological processes, from plant defense and stress responses to growth regulation and development, has been documented across plant species. OPDA is synthesized in the plastids from alpha-linolenic acid, and OPDA binding to plastidial cyclophilins activates TGA transcription factors upstream of genes associated with stress responses. Here, we summarize what is known about OPDA metabolism and signaling while briefly discussing its jasmonate dependent and independent roles. We also describe open questions, such as the OPDA protein interactome and biological roles of OPDA conjugates.

Publication types

Review