Model Dynamics and Optimal Control for Intervention Policy of COVID-19 Epidemic with Quarantine and Immigrating Disturbances

Bull Math Biol. 2022 Sep 17;84(11):122. doi: 10.1007/s11538-022-01080-w.

Abstract

A dynamic model called SqEAIIR for the COVID-19 epidemic is investigated with the effects of vaccination, quarantine and precaution promotion when the traveling and immigrating individuals are considered as unknown disturbances. By utilizing only daily sampling data of isolated symptomatic individuals collected by Mexican government agents, an equivalent model is established by an adaptive fuzzy-rules network with the proposed learning law to guarantee the convergence of the model's error. Thereafter, the optimal controller is developed to determine the adequate intervention policy. The main theorem is conducted to demonstrate the setting of all designed parameters regarding the closed-loop performance. The numerical systems validate the efficiency of the proposed scheme to control the epidemic and prevent the overflow of requiring healthcare facilities. Moreover, the sufficient performance of the proposed scheme is achieved with the effect of traveling and immigrating individuals.

Keywords: COVID-19; Discrete-time systems; Fuzzy rules emulated networks; Impulsive disturbance; Optimal control; SqEAIIR model.

MeSH terms

  • Algorithms
  • COVID-19* / epidemiology
  • COVID-19* / prevention & control
  • Computer Simulation
  • Feedback
  • Humans
  • Mathematical Concepts
  • Models, Biological
  • Neural Networks, Computer
  • Nonlinear Dynamics
  • Policy
  • Quarantine*