Demographic reporting across a decade of neuroimaging: a systematic review

Brain Imaging Behav. 2022 Dec;16(6):2785-2796. doi: 10.1007/s11682-022-00724-8. Epub 2022 Sep 17.

Abstract

Diversity of participants in biomedical research with respect to race, ethnicity, and biological sex is crucial, particularly given differences in disease prevalence, recovery, and survival rates between demographic groups. The objective of this systematic review was to report on the demographics of neuroimaging studies using magnetic resonance imaging (MRI). The Web of Science database was used and data collection was performed between June 2021 to November 2021; all articles were reviewed independently by at least two researchers. Articles utilizing MR data acquired in the United States, with n ≥ 10 human subjects, and published between 2010-2020 were included. Non-primary research articles and those published in journals that did not meet a quality control check were excluded. Of the 408 studies meeting inclusion criteria, approximately 77% report sex, 10% report race, and 4% report ethnicity. Demographic reporting also varied as function of disease studied, participant age range, funding, and publisher. We anticipate quantitative data on the extent, or lack, of reporting will be necessary to ensure inclusion of diverse populations in biomedical research.

Keywords: Demographic reporting; MRI; NIH Revitalization Act of 1993; Neuroimaging.

Publication types

  • Systematic Review
  • Review

MeSH terms

  • Ethnicity*
  • Humans
  • Magnetic Resonance Imaging*
  • United States