Paraglottic space schwannoma: a case report and literature review

J Int Med Res. 2022 Sep;50(9):3000605221122497. doi: 10.1177/03000605221122497.

Abstract

Neurogenic tumors located in the larynx are extremely rare. Among them, schwannoma is a benign encapsulated tumor originating from Schwann cells, which form nerve fiber sheaths in the peripheral nervous system. We herein report a case of a schwannoma arising from a rare subsite of the larynx and review the literature on laryngeal schwannoma. The case involved a woman with a 1-month history of globus pharyngeus and dysphagia without dysphonia. Rigid laryngoscopy and magnetic resonance imaging showed a large submucosal bulge toward the medial wall of the right pyriform fossa, pushing the right false and true vocal cords and aryepiglottic fold inward. A transcervical approach was used to completely excise the tumor without incisional biopsy or preliminary tracheotomy. Histology confirmed a benign schwannoma originating from the right paraglottic space, which was extremely rare. During follow-up, no evidence of recurrence or a residual mass was found. The transcervical approach is a useful and less invasive treatment for laryngeal schwannoma located in the paraglottic space.

Keywords: Larynx; benign tumor; case report; paraglottic space; schwannoma; transcervical approach.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Female
  • Hoarseness / etiology
  • Humans
  • Laryngeal Neoplasms* / pathology
  • Laryngoscopy
  • Larynx* / pathology
  • Neurilemmoma* / complications
  • Neurilemmoma* / diagnostic imaging
  • Neurilemmoma* / surgery