Comparative Evaluation of Salivary and Serum High-Sensitive C-Reactive Protein in Acute Myocardial Infarction

K Sakthi SaranyaDevi; B Sasi Rekha; J Vijay Thiyagarajan; R Dhivya; Suriyahanth Mihiran; S Santhosh

doi:10.4103/jpbs.jpbs_845_21

Comparative Evaluation of Salivary and Serum High-Sensitive C-Reactive Protein in Acute Myocardial Infarction

J Pharm Bioallied Sci. 2022 Jul;14(Suppl 1):S127-S130. doi: 10.4103/jpbs.jpbs_845_21. Epub 2022 Jul 13.

Authors

K Sakthi SaranyaDevi¹, B Sasi Rekha¹, J Vijay Thiyagarajan², R Dhivya³, Suriyahanth Mihiran⁴, S Santhosh⁵

Affiliations

¹ Department of Oral Medicine and Radiology, J.K.K. Nattraja Dental College and Hospitals, Namakkal, Tamil Nadu, India.
² Department of Oral and Maxillofacial Surgery, J.K.K. Nattraja Dental College and Hospitals, Namakkal, Tamil Nadu, India.
³ Department of Periodontics, J.K.K. Nattraja Dental College and Hospitals, Namakkal, Tamil Nadu, India.
⁴ Department of Oral and Maxillofacial Surgery, K.S.R. Institute of Dental Science and Research, Tiruchengode, Tamil Nadu, India.
⁵ Department of Periodontics, JKKN Dental College and Hospital, Namakkal, Tamil Nadu, India.

Abstract

Aim: The aim of this study is to comparatively evaluate the serum and salivary high-sensitive C-reactive protein (hs-CRP) in patients with acute myocardial infarction (MI).

Subjects and methods: The study group consisted of 60 patients of whom 30 were MI patients and 30 were controls. Serum hs-CRP was assessed using particle-enhanced immunoturbidimetric assay. Saliva hs-CRP is determined using a microplate reader cum UV photospectrometer from BMG.

Results: In this study, levels of both serum and salivary hs-CRP in control and MI patients showed a positive correlation. Saliva can be used as an alternative biofluid to determine hs-CRP in MI patients.

Conclusion: Saliva can be used as a alternative biofluid to determine the risk as well as to determine prognosis in acute myocardial infarction.

Keywords: C-reactive protein; high-sensitive C-reactive protein; myocardial infarction; salivary C-reactive protein; salivary biomarkers; serum C-reactive protein.