Successful utilization of high frequency spinal cord stimulation for HIV and chemotherapy induced polyneuropathy

Pain Manag. 2022 Oct;12(7):805-811. doi: 10.2217/pmt-2021-0125. Epub 2022 Sep 15.

Abstract

We present a case of a 53-year-old male who presented with functionally limiting bilateral lower extremity neuropathic pain secondary to multiple subtypes of small fiber neuropathy. He had failed management with multiple conservative measures including oral medications, physical therapy and desensitization techniques. He ultimately underwent placement of a spinal cord stimulator and continued to experience 80% improvement of his pain, as well as improved function and quality of life at 5 month follow-up. To our knowledge, this is the first reported case of successful treatment of multiple subtypes of small fiber neuropathy with spinal cord stimulator.

Keywords: HIV neuropathy; chemotherapy induced neuropathy; high frequency spinal cord stimulation; neuromodulation; polyneuropathy; small fiber neuropathy; spinal cord stimulation.

Plain language summary

We report a case of a 53-year-old male who presented with multiple subtypes of small fiber neuropathy, characterized by abnormal sensation and nerve pain in his distal lower extremities, which was making performing his activities of daily living challenging. He had failed multiple conservative measures including oral medications, physical therapy and desensitization techniques. The patient then underwent a trial with a spinal cord stimulator, which includes placing a device in the spinal canal that can alleviate pain by providing low levels of electrical current. At the 5 month follow-up, he continued to report 80% improvement of his pain as well as improved function and quality of life. This is the first reported use of spinal cord stimulator in a patient with multiple subtypes of small fiber neuropathy.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents*
  • HIV Infections* / complications
  • HIV Infections* / drug therapy
  • Humans
  • Male
  • Middle Aged
  • Neuralgia* / chemically induced
  • Neuralgia* / complications
  • Neuralgia* / therapy
  • Polyneuropathies* / chemically induced
  • Polyneuropathies* / complications
  • Polyneuropathies* / therapy
  • Quality of Life
  • Small Fiber Neuropathy* / complications
  • Spinal Cord
  • Spinal Cord Stimulation* / methods

Substances

  • Antineoplastic Agents