Rhodamine-based cyclic hydrazide derivatives as fluorescent probes for selective and rapid detection of formaldehyde

Sung Yeon Kim; Sang-Hyun Park; Chang-Hee Lee; Jinsung Tae; Injae Shin

doi:10.1039/d2ra02104h

Rhodamine-based cyclic hydrazide derivatives as fluorescent probes for selective and rapid detection of formaldehyde

RSC Adv. 2022 Aug 11;12(35):22435-22439. doi: 10.1039/d2ra02104h. eCollection 2022 Aug 10.

Authors

Sung Yeon Kim¹, Sang-Hyun Park¹, Chang-Hee Lee¹, Jinsung Tae¹, Injae Shin¹

Affiliation

¹ Department of Chemistry, Yonsei University Seoul 03722 Republic of Korea injae@yonsei.ac.kr jstae@yonsei.ac.kr.

Abstract

We describe fluorescent probes to detect formaldehyde (FA) in aqueous solutions and cells. The probes rapidly respond to FA in aqueous solutions and have great selectivity toward FA over other biologically relevant analytes. The results of cell studies reveal that probe 1 can be utilized to monitor endogenous and exogenous FA in live cells.