A Suspected Case of Multisystem Inflammatory Disease in Children Following COVID-19 Vaccination: A Case Report and Systematic Literature Review

Pediatr Infect Dis J. 2022 Nov 1;41(11):e456-e460. doi: 10.1097/INF.0000000000003674. Epub 2022 Aug 25.

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is rare but can be a potentially serious complication following SARS-CoV-2 infection in children. 1 Introduction of coronavirus disease 2019 (COVID-19) vaccines are effective in lowering the burden due to SARS-CoV-2. However, there have been reports of MIS occurrence following COVID-19 vaccination in adults. 2 The potential public health implication of MIS-C following COVID-19 vaccination is not clear in children. Our objective is to describe the spectrum of clinical disease, therapy, and outcomes of MIS-C following COVID-19 vaccination in children.

Publication types

  • Case Reports
  • Systematic Review

MeSH terms

  • Adult
  • COVID-19 Vaccines* / adverse effects
  • COVID-19* / complications
  • COVID-19* / prevention & control
  • Child
  • Humans
  • SARS-CoV-2
  • Systemic Inflammatory Response Syndrome / chemically induced
  • Systemic Inflammatory Response Syndrome / diagnosis
  • Vaccination / adverse effects

Substances

  • COVID-19 Vaccines

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related