The importance of phenoconversion when using the CYP2D6 genotype in clinical practice

Pharmacogenomics. 2022 Sep;23(14):749-752. doi: 10.2217/pgs-2022-0087. Epub 2022 Sep 14.

Abstract

Tweetable abstract Clinical phenoconversion needs to be incorporated when interpreting and applying CYP2D6 results in clinical care. This article describes how this can be performed either manually or by utilizing online tools and resources. #Phenoconversion #Pharmacogenomics.

Keywords: CYP2D6; drug interaction; pharmacist; pharmacogenetics; pharmacogenomics; phenoconversion.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Cytochrome P-450 CYP2D6* / genetics
  • Genotype
  • Humans
  • Pharmacogenetics*

Substances

  • Cytochrome P-450 CYP2D6