Generation of single-sex litters in laboratory rodents: Caution for unintended outcomes and potential shortcomings

Giovanni Laviola; Walter Adriani

doi:10.1016/j.neubiorev.2022.104866

Generation of single-sex litters in laboratory rodents: Caution for unintended outcomes and potential shortcomings

Neurosci Biobehav Rev. 2022 Nov:142:104866. doi: 10.1016/j.neubiorev.2022.104866. Epub 2022 Sep 10.

Authors

Giovanni Laviola¹, Walter Adriani²

Affiliations

¹ Center for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, I-00161 Rome, Italy. Electronic address: giovanni.laviola@iss.it.
² Center for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, I-00161 Rome, Italy.

PMID: 36100113
DOI: 10.1016/j.neubiorev.2022.104866

No abstract available

Keywords: Animal welfare; Developmental sexual segregation; Early experiences; Phenotypic variability; Reproducibility; Sibling effect; Social heterogeneity; Three Rs; Translation.

Publication types

Review

MeSH terms

Animals
Rodentia*