Pectin-type polysaccharide from galangal: An efficient emulsifier to construct the emulsion-based delivery system for galangal flavonoids

Int J Biol Macromol. 2022 Nov 30:221:644-652. doi: 10.1016/j.ijbiomac.2022.09.051. Epub 2022 Sep 12.

Abstract

Galangal is rich in flavonoids and polysaccharides but underutilized. In this study, galangal flavonoids and polysaccharides (GP-HN and GP-UN) were obtained by segmented extraction, used for chemical composition determination/structural characterization, and constructed for the emulsion delivery system. The results showed that galangin accounted for 71.45 % of total flavonoids. GP-HN and GP-UN were prepared by enzymatic-assisted high-temperature and ultrasonic extraction, which were low-molecular-weight pectin-type polysaccharides mainly constructed by galacturonic acid, galactose, and arabinose. GP-UN was the best emulsifier due to interfacial activities, emulsifying properties, interfacial resistance to bile salts displacement abilities, and anti-lipid digestion abilities of GPs. GP-UN emulsion could stably deliver flavonoids. This study presented a method for orderly reorganizing flavonoids and polysaccharides, guiding for utilization of whole bioactive components in galangal.

Keywords: Emulsifier; Galangal; Pectin-type polysaccharides.

MeSH terms

  • Emulsifying Agents* / chemistry
  • Emulsions / chemistry
  • Flavonoids
  • Pectins* / chemistry
  • Polysaccharides / chemistry

Substances

  • Pectins
  • Emulsions
  • Emulsifying Agents
  • Polysaccharides
  • Flavonoids